Lynn W. Enquist

This study shows PRV hijacks DDX3X in sensory neurons to cause 'mad itch' and immune suppression, aiding viral spread.

This study identifies US3 kinase's role in promoting retrograde transport of nucleocapsids in axons via Akt/mToRC1 signaling during alpha herpesvirus infection.

This study shows that the Us9 protein of pseudorabies virus regulates axonal sorting differently in immature versus mature neurons, with immature neurons showing reduced Us9-dependent sorting and increased Us9-independent transport.

The paper identifies small herpesvirus latency-associated promoters that enable long-term, pan-neuronal transgene expression in the CNS using AAV vectors.

The paper describes a computational framework to convert high-throughput DNA sequencing data into neural circuit connectivity using BOINC and applies it to pseudorabies virus experiments.