Jessica L. Verpeut

Elucidating the Role of Cerebellar Nuclei Parvalbumin Activity on Adolescent Reversal Learning

This study investigates the role of cerebellar nuclei parvalbumin activity in adolescent reversal learning using DREADDs and Hapln1-AAV vectors in mice.

Structural covariation between cerebellum and cerebral cortex is atypically modulated by thalamus in autism spectrum disorder

The paper investigates structural covariation between cerebellum, thalamus, and cerebral cortex in neurotypical and ASD children, finding altered coupling patterns in ASD.

Cerebellar contributions to a brainwide network for reversal learning

This paper investigates cerebellar contributions to reversal learning by mapping brainwide networks through c-Fos activation and identifies distinct effects of lobule VI and crus I inactivation.

Adeno-associated virus (AAV) reduces cortical dendritic complexity in a TLR9-dependent manner

This study shows that AAV triggers dendritic complexity loss in the cortex via TLR9, independent of capsid or transgene, and identifies TLR9 inhibitors as potential safety improvements.

Homologous organization of cerebellar pathways to sensory, motor, and associative forebrain

The paper maps cerebellar pathways to forebrain regions using tracing viruses and quantitative analysis, revealing homologous networks linking cerebellar areas to sensory, motor, and associative forebrain targets.

Deep behavioral phenotyping of mouse autism models using open-field behavior

This paper develops a deep learning framework to analyze mouse behavior in the open field test, revealing distinct adaptation patterns in autism models.

SMALL ALPHAHERPESVIRUS LATENCY-ASSOCIATED PROMOTERS DRIVE EFFICIENT AND LONG-TERM TRANSGENE EXPRESSION IN THE CENTRAL NERVOUS SYSTEM

The paper identifies small herpesvirus latency-associated promoters that enable long-term, pan-neuronal transgene expression in the CNS using AAV vectors.