Author

Sandeep Sundara Rajan

Wellcome Sanger InstituteORCID 0000-0001-9993-3182Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Organism:mouse· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

Anastasia Kavasakali· 1 shared Andrea BertottiiD· 1 shared Angham Al SaediiD· 1 shared Benjamin SchwartziD· 1 shared Brian T. JonesiD· 1 shared Camille FourneauxiD· 1 shared Cansu DinçeriD· 1 shared Christophe D. ProulxiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperCancer Biology

Anastasia Kavasakali

Mutual co-authors in cluster

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintFeb 23, 2026

CRISPR/CAS9-MEDIATED LOSS OF VESICULAR GLUTAMATE TRANSPORTER IN SEROTONIN NEURONS OF THE DORSAL RAPHE NUCLEUS LEADS TO SYNAPTIC CHANGES AND ANXIETY-LIKE BEHAVIORS

Lydia Saidi, Véronique Rioux, Marie‐Josée Wallman…·Martin Parent

This study investigates the role of VGluT3 in DRN 5-HT neurons by manipulating its expression and assesses effects on synaptic structure and behavior.

DOI 10.64898/2026.02.23.707446

mouseexperimental assay

𝕏 PostBluesky

Cancer BiologybioRxivPreprintDec 27, 2025

On-target mutations confer resistance to WRN helicase inhibitors in Microsatellite Unstable Cancer Cells.

Gabriele Picco, Yanhua Rao, Angham Al Saedi…·Mathew J. Garnett

This study identifies on-target WRN mutations as resistance mechanisms in MSI cancer cells to WRN helicase inhibitors and suggests combination therapies to prevent resistance.

3 citations

humanwhole-exome sequencing

𝕏 PostBluesky