Author

Camille Fourneaux

Wellcome Sanger InstituteORCID 0000-0002-4902-2310Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Cancer Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Research Focus:benchmarking· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Gabriele PiccoiD· 2 shared Mathew J. GarnettiD· 2 shared Amanda J. OliveriD· 1 shared Anastasia Kavasakali· 1 shared Andrea BertottiiD· 1 shared Angham Al SaediiD· 1 shared Arnaud BonnaffouxiD· 1 shared Benjamin SchwartziD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersGenomics

Gabriele PiccoORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Perturbation-guided mapping of colorectal cancer cell states to causal mechanisms

Soroor Hediyeh-zadeh, Tzen S. Toh, Olli Dufva, Giuseppe Serra, Rashika Jakhmola, Camille Fourneaux, Gonçalo Pinto, Zijian Fang, Gabriele Picco, Amanda J. Oliver, Rasa Elmentaite, Till Richter, Ken To, J. Patrick Pett, Sarah Amalia Teichmann, , Mathew J. Garnett

This paper develops a continual learning framework to map colorectal cancer cell states to causal mechanisms through integration of single-cell data and perturbation experiments.

bioRxiv · Mar 24, 2026 · PreprintGenomics

On-target mutations confer resistance to WRN helicase inhibitors in Microsatellite Unstable Cancer Cells.

Gabriele Picco, Yanhua Rao, Angham Al Saedi, Samantha J. Walker, Shriram G. Bhosle, Yang Lee, Sara F. Vieira, María Ana García-Casado, Gilberto Valdes Garcia, Kieron May, Francesco Paolo Sassi, Inigo Barrio Hernandez, Mamta Sharma, Cansu Dinçer, Theo Bell, , Mathew J. Garnett

This study identifies on-target WRN mutations as resistance mechanisms in MSI cancer cells to WRN helicase inhibitors and suggests combination therapies to prevent resistance.

bioRxiv · Dec 27, 2025 · PreprintCancer Biology

TopoDoE: A Design of Experiment strategy for selection and refinement in ensembles of executable Gene Regulatory Networks

Matteo Bouvier, Souad Zreika, Elodie Vallin, Camille Fourneaux, Sandrine Gonin-Giraud, Arnaud Bonnaffoux, Olivier Gandrillon

The paper introduces a Design of Experiment strategy to refine Gene Regulatory Networks by selecting informative perturbations and validating predictions against experimental data.

BMC Bioinformatics · Jul 19, 2024Peer-reviewedBioinformatics