Paola G. Bronson

This study identifies a BACH2-NRF2 axis regulating fetal hemoglobin activation through genetic and functional analyses in a large multi-ancestry cohort.

This study identifies six genes associated with hand grip strength using rare protein-coding variants in 340,319 individuals and shows additive effects with common variants.

The paper performs single-variant and gene-based association analyses of 4,529 phenotypes using exome data from 426,370 UK Biobank individuals, finding associations linked to variant frequency and deleteriousness.

The paper maps eQTLs during T cell activation and identifies immune disease risk variants that regulate gene expression dynamics, showing colocalization with disease-associated genes.

This study shows that higher genetic risk burden for multiple sclerosis is associated with earlier disease onset.

This study uses Mendelian randomization to identify plasma proteins associated with stroke risk and potential therapeutic targets.

The paper describes exome sequencing of 200,643 UK Biobank participants, providing a rich resource of coding variants for genetic and drug discovery research.

The paper identifies T cell states associated with immune disease variants by analyzing chromatin activity across different activation states.

This study identifies neurology-related proteins in plasma associated with cognitive ability and brain volume in older adults, with partial mediation by brain volume.