Author

Mahesh N. Sangrithi

King's College LondonORCID 0000-0002-0008-4588Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

Daniel M. SnelliD· 2 shared Prabhakaran MunusamyiD· 2 shared Afshan McCarthyiD· 1 shared Ahmed Abdelbaki· 1 shared Alice E. Chen· 1 shared Aurélien CourtoisiD· 1 shared Carlos M Abascal Sherwell Sanchez· 1 shared Claire E. SenneriD· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersDevelopmental Biology

Daniel M. SnellORCID

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3 papers

Recent·Most cited

Developmental BiologybioRxivPreprintNov 26, 2024

Sex chromosomes shape the transcriptional landscape of the preimplantation mouseembryo

Daniel M. Snell, Wazeer Varsally, Aurélien Courtois…·James M. A. Turner

This study shows sex chromosomes significantly shape the transcriptional landscape of preimplantation mouse embryos through various mechanisms including Y chromosome effects, X chromosome dosage, imprinting, and Xist.

1 citation

mousescRNA-seq

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Developmental BiologyDevelopmentPeer-reviewedSep 1, 2024

Transcription factor-based transdifferentiation of human embryonic to trophoblast stem cells

Paula A. Balestrini, Ahmed Abdelbaki, Afshan McCarthy…·Norah M. E. Fogarty

The paper identifies transcription factors that can convert human embryonic stem cells into trophoblast stem cells, revealing their role in early placental development.

11 citations

humanbulk RNA-seq

𝕏 PostBluesky

Developmental BiologybioRxivPreprintNov 6, 2023

Single cell RNA-seq reveals protracted germ line X chromosome reactivation dynamics directed by a PRC2 dependent mechanism

Yaqiong Liu, Xianzhong Lau, Munusamy Prabhakaran…·Mahesh N. Sangrithi

The paper uses single-cell RNA-seq and chromatin profiling to study X chromosome reactivation dynamics in mouse germ cells, showing gradual reactivation and PRC2-dependent regulation.

1 citation

mousescRNA-seq

𝕏 PostBluesky