Author
Harvard UniversityORCID 0000-0002-0021-0476Unclaimed ORCID profile · follow to get notified of new preprints
6 papers
Recent·Most cited
Ernst W. Schmid, Helen Zhu, Eunjin Ryu…·Johannes C. Walter
The paper develops a computational pipeline to predict human protein-protein interactions, identifying 16,000 high-confidence interactions, many previously unknown or structurally unresolved.
Sophia Fochler, Matthew H. Doran, Tom Beneke…·Richard John Wheeler
This study identifies specific dynein contributions to flagellar beat types in Leishmania, challenging the existing model of dynein function in flagellar beating.
Sven M. Lange, Jeremy A. Bennett, Robyn J. Eisert, Alan Brown
This study identifies a mechanism by which polyubiquitinated proteins are retrieved from cilia via a CFAP36-ARL3 complex linked to retrograde IFT trains.
Daniel O Dodd, Sabrina Méchaussier, Patricia Levy Yeyati…·Pleasantine Mill
The paper identifies TUBB4B mutations causing distinct ciliopathic diseases by affecting microtubule dynamics and cilia formation in humans and mice.
Kiarash Jamali, Lukas Käll, Rui Zhang…·Sjors H. W. Scheres
ModelAngelo combines convolutional and graph neural networks with protein language model embeddings and hidden Markov model searches to automate atomic model building and identify unknown proteins in cryo-EM maps.
Meng Zhang, Miao Gui, Zifu Wang…·Gerhard Wagner
The paper reports cryo-EM structures of a GPCR-G protein complex in lipid nanodiscs, revealing structural insights into G protein activation without stabilizing agents.