Author

Sven M. Lange

University of DundeeORCID 0000-0002-6011-8647Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Organism:yeast· 1

Frequent Co-Authors

Melanie Wightman· 2 shared Alan BrowniD· 1 shared Alan R. PrescottiD· 1 shared Alexia F. KalogeropulouiD· 1 shared Cristian Polo RiveraiD· 1 shared Dario R. AlessiiD· 1 shared Elena PurlyteiD· 1 shared Esther M. SammleriD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersBiochemistry

Melanie Wightman

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Molecular BiologyCellPeer-reviewedAug 21, 2025

A conserved mechanism for the retrieval of polyubiquitinated proteins from cilia

Sven M. Lange, Jeremy A. Bennett, Robyn J. Eisert, Alan Brown

This study identifies a mechanism by which polyubiquitinated proteins are retrieved from cilia via a CFAP36-ARL3 complex linked to retrograde IFT trains.

11 citationstop 2%

experimental assay

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BiochemistryScience AdvancesPeer-reviewedJun 7, 2024

Mechanism of human PINK1 activation at the TOM complex in a reconstituted system

Olawale G. Raimi, Hina Ojha, Kenneth Ehses…·Miratul M. K. Muqit

This study identifies TOM20, TOM70, TOM40, and associated subunits as critical for PINK1 activation in a reconstituted yeast system, providing insights for PINK1 activator development.

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yeastexperimental assay

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NeuroscienceBiochemical JournalPeer-reviewedAug 11, 2022

Impact of 100 LRRK2 variants linked to Parkinsons Disease on kinase activity and microtubule binding

Alexia F. Kalogeropulou, Elena Purlyte, Francesca Tonelli…·Dario R. Alessi

This study evaluates 100 LRRK2 variants linked to Parkinson's disease, identifying those that enhance kinase activity and microtubule binding, and highlights their implications for clinical trials.

130 citationstop 1%

humanproteomics

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