Author

Maria Passafaro

National Research CouncilORCID 0000-0002-0045-5676Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:rat· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Assay:scRNA-seq· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Edoardo MorettoiD· 2 shared Federico MiozzoiD· 2 shared Andrzej W. CwetschiD· 1 shared Anna LongattiiD· 1 shared Annalaura Zambrano Avendano· 1 shared Annalisa SavardiiD· 1 shared Antonio G. ZippoiD· 1 shared Bruno PintoiD· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersNeuroscience

Edoardo MorettoORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Disruption of autism-associated Pcdh9 gene leads to transcriptional alterations, synapses overgrowth and aberrant excitatory transmission in the CA1

Federico Miozzo, Luca Murru, Greta Maiellano, Ilaria di Iasio, Antonio G. Zippo, Annalaura Zambrano Avendano, Verjinia D. Metodieva, Sara Riccardi, Deborah D’Aliberti, Silvia Spinelli, Tamara Canu, Linda Chaabane, Shinji Hirano, Martien J. Kas, Maura Francolini, , Maria Passafaro

This study shows that Pcdh9 deletion in mice causes synaptic overgrowth and excitatory transmission defects in the hippocampus, revealing its role in synaptic morphology and function.

Journal of Neuroscience · Nov 18, 2024Peer-reviewedNeuroscience

The tetraspanin TSPAN5 regulates AMPARs exocytosis by interacting with the AP-4 complex

Edoardo Moretto, Anna Longatti, Federico Miozzo, Caroline Bonnet, Françoise Coussen, Fanny Jaudon, Lorenzo A. Cingolani, Maria Passafaro

The paper identifies TSPAN5 as an adaptor protein that promotes AMPA receptor exocytosis by interacting with AP-4 and Stargazin in rat hippocampal neurons.

eLife · Jan 30, 2023Peer-reviewedNeuroscience

A Rat Model of a Focal Mosaic Expression of PCDH19 Replicates Human Brain Developmental Abnormalities and Behaviors

Andrzej W. Cwetsch, Ilias Ziogas, Roberto Narducci, Annalisa Savardi, Maria Bolla, Bruno Pinto, Laura E. Perlini, Silvia Bassani, Maria Passafaro, Laura Cancedda

This study creates a rat model with focal mosaic Pcdh19 expression, replicating brain developmental abnormalities and behaviors seen in human EIEE9.

Brain Communications · Apr 5, 2022Peer-reviewedNeuroscience