Author

Tamara Canu

IRCCS Ospedale San RaffaeleORCID 0000-0002-4589-9377Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Agostina Di PizioiD· 1 shared Angelo IannielliiD· 1 shared Annalaura Zambrano Avendano· 1 shared Antonio EspositoiD· 1 shared Antonio G. ZippoiD· 1 shared Deborah D’AlibertiiD· 1 shared Edoardo MorettoiD· 1 shared Elisa VenturaiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperBioengineering

Agostina Di PizioORCID

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2 papers

Recent·Most cited

Targeted and efficient AAV therapy for neuroblastoma via direct capsid-antibody coupling

Mirko Luoni, Serena Gea Giannelli, Stefano Parracino, Francesca Morosi, Elisa Ventura, Agostina Di Pizio, Sharon Muggeo, Angelo Iannielli, Tamara Canu, Tommaso Russo, Antonio Esposito, Fabio Pastorino, Vania Broccoli

This paper develops AAV-STITCH, a method to target neuroblastoma cells using anti-GD2 ScFv coupled to AAV capsids, showing selective transduction and tumor suppression in mouse models.

bioRxiv · Nov 12, 2025 · PreprintBioengineering

Disruption of autism-associated Pcdh9 gene leads to transcriptional alterations, synapses overgrowth and aberrant excitatory transmission in the CA1

Federico Miozzo, Luca Murru, Greta Maiellano, Ilaria di Iasio, Antonio G. Zippo, Annalaura Zambrano Avendano, Verjinia D. Metodieva, Sara Riccardi, Deborah D’Aliberti, Silvia Spinelli, Tamara Canu, Linda Chaabane, Shinji Hirano, Martien J. Kas, Maura Francolini, , Maria Passafaro

This study shows that Pcdh9 deletion in mice causes synaptic overgrowth and excitatory transmission defects in the hippocampus, revealing its role in synaptic morphology and function.

Journal of Neuroscience · Nov 18, 2024Peer-reviewedNeuroscience