Author

Edoardo Moretto

National Research CouncilORCID 0000-0002-3546-6797Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Assay:proteomics· 1 Organism:rat· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Federico MiozzoiD· 2 shared Maria PassafaroiD· 2 shared Anna LongattiiD· 1 shared Annalaura Zambrano Avendano· 1 shared Antonio G. ZippoiD· 1 shared Caroline Bonnet· 1 shared Chiara PanziiD· 1 shared Deborah D’AlibertiiD· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersNeuroscience

Federico MiozzoORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Disruption of autism-associated Pcdh9 gene leads to transcriptional alterations, synapses overgrowth and aberrant excitatory transmission in the CA1

Federico Miozzo, Luca Murru, Greta Maiellano, Ilaria di Iasio, Antonio G. Zippo, Annalaura Zambrano Avendano, Verjinia D. Metodieva, Sara Riccardi, Deborah D’Aliberti, Silvia Spinelli, Tamara Canu, Linda Chaabane, Shinji Hirano, Martien J. Kas, Maura Francolini, , Maria Passafaro

This study shows that Pcdh9 deletion in mice causes synaptic overgrowth and excitatory transmission defects in the hippocampus, revealing its role in synaptic morphology and function.

Journal of Neuroscience · Nov 18, 2024Peer-reviewedNeuroscience

Botulinum neurotoxin A modulates the axonal release of pathological tau in hippocampal neurons

Chiara Panzi, Sunaina Surana, Samantha De La‐Rocque, Edoardo Moretto, Oscar M. Lazo, Giampietro Schiavo

This study investigates how botulinum neurotoxin A affects the release of mutant tau in hippocampal neurons, showing it blocks mutant tau release by modulating SNAP25.

Toxicon · Apr 8, 2023Peer-reviewedNeuroscience

The tetraspanin TSPAN5 regulates AMPARs exocytosis by interacting with the AP-4 complex

Edoardo Moretto, Anna Longatti, Federico Miozzo, Caroline Bonnet, Françoise Coussen, Fanny Jaudon, Lorenzo A. Cingolani, Maria Passafaro

The paper identifies TSPAN5 as an adaptor protein that promotes AMPA receptor exocytosis by interacting with AP-4 and Stargazin in rat hippocampal neurons.

eLife · Jan 30, 2023Peer-reviewedNeuroscience