ImmunologybioRxivPreprint
Targeting Impaired Type I Interferon IL-27 Signaling Rescues T Regulatory Cell Suppressive Function in Relapsing-Remitting Multiple Sclerosis
Manal Elzoheiry, Maryamsadat Seyedsadr, John A. Wrobel…·Silva Markovic‐Plese
This study identifies impaired type I IFN and IL-27 signaling in RRMS Tregs and shows that cGAMP-MPs restore Treg suppressive function in EAE.