Concomitant acetylation and loading of H2A.Z by NuA4/TIP60 regulate target gene transcription
Amel Mameri, Catherine Lachance, Claudia Cattoglio, Stéphanie Bianco, Jonathan Humbert, Charles Joly-Beauparlant, Emeric Texeraud, Arul Banerjea, Anahita Lashgari, Jean‐Philippe Lambert, Samer M. I. Hussein, Arnaud Droit, Jacques Côté
This study investigates how NuA4/TIP60 complex acetylates and loads H2A.Z onto chromatin to regulate transcription, showing that acetylation precedes chromatin incorporation at promoters.
bioRxiv · Sep 22, 2025 · PreprintMolecular Biology