Atypical Protein Kinase C iota (PKC{lambda}/{iota}) Ensures Mammalian Development by Establishing the Maternal-Fetal Exchange Interface
Bhaswati Bhattacharya, Pratik Home, Avishek Ganguly, Soma S. Ray, Ananya Ghosh, Md. Rashedul Islam, Valerie A. French, Courtney A. Marsh, Sumedha Gunewardena, Hiroaki Okae, Takahiro Arima, Soumen Paul
This study identifies PKCλ/ι as essential for trophoblast progenitor differentiation into syncytiotrophoblast cells during placentation in both mice and humans.
Proceedings of the National Academy of Sciences · Jun 8, 2020Peer-reviewedDevelopmental Biology