Author

Elsy M. Ngwa

Boston Children's HospitalORCID 0000-0002-0104-6700Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Research Focus:development & morphogenesis· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Organism:bacteria (other)· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

Jay R. ThiagarajahiD· 3 shared Krishnan RaghunathaniD· 3 shared Clara BaekiD· 2 shared Eranthie WeerapanaiD· 2 shared José Ordovás-MontañésiD· 2 shared Qianni PengiD· 2 shared Scott B. SnapperiD· 2 shared Aaron J. MauraisiD· 1 shared

Activity by Year

2025-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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3 shared papersCell Biology

Jay R. ThiagarajahORCID

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3 papers

Recent·Most cited

Developmental BiologybioRxivPreprintDec 17, 2025

Development of the Early Childhood Duodenum across Ancestry, Geography and Environment

Joshua de Sousa Casal, Krishnan Raghunathan, Chelsea Asare…·Jay R. Thiagarajah

The paper creates a cellular and spatial map of the duodenum in children, revealing environmental and developmental influences on intestinal cell states.

1 citation

humanscRNA-seq

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Cell BiologyNature CommunicationsPeer-reviewedNov 28, 2025

A niche-dependent redox rheostat regulates epithelial stem cell fate in the distal colon

Xi Chen, Krishnan Raghunathan, Bin Bao…·Jay R. Thiagarajah

This study shows that redox balance, regulated by NOX1 and HIF1-IDH1 interactions, controls epithelial stem cell fate in the distal colon niche.

4 citations

mouseproteomics

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Cell BiologybioRxivPreprintMay 9, 2025

Trans-kingdom coupling of redox signaling to environmental cell stress responses through multiphase partitioning.

Elsy M. Ngwa, Xi Chen, Stefanie S. Schmieder…·Jay R. Thiagarajah

This paper identifies RACK1 as a redox-regulated hub that coordinates cellular stress responses through condensate-based microdomains, linking environmental stress to immune signaling and translational control.

DOI 10.1101/2025.05.09.653213

humanbacteria (other)

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