Qianni Peng

This study shows that redox balance, regulated by NOX1 and HIF1-IDH1 interactions, controls epithelial stem cell fate in the distal colon niche.

This study shows hydrogen sulfide increases intracellular oxygen and destabilizes HIF-1, altering hypoxia sensing and potentially contributing to O2 toxicity diseases.

This paper identifies RACK1 as a redox-regulated hub that coordinates cellular stress responses through condensate-based microdomains, linking environmental stress to immune signaling and translational control.