Author

Joshua de Sousa Casal

Broad InstituteORCID 0000-0003-2006-3992Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Developmental Biology· 2 Systems Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 3 Organism:human· 3 Assay:scRNA-seq· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Research Focus:database / resource· 1 Approach:deep learning· 1

Frequent Co-Authors

Daniel ZeveiD· 2 shared José Ordovás-MontañésiD· 2 shared Abdalla AhmediD· 1 shared Abigail Plone· 1 shared Adam R. Greene· 1 shared Adrienne LuomaiD· 1 shared Agne AntanaviciuteiD· 1 shared Albert BurgeriD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersDevelopmental Biology

Daniel ZeveORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Systems BiologybioRxivPreprintOct 12, 2026

The Human Gut Cell Atlas v1.0: A Unified, Community-Built Reference of Cellular Diversity Across the Gut

Kyle Kimler, Christopher Lance, Balázs Bohár…·Kathryn E. Hamilton

The paper presents the Human Gut Cell Atlas v1.0, a unified reference of gut cell diversity, revealing how tissue structure influences cellular composition and enabling disease and organoid analysis.

DOI 10.64898/2026.10.09.753994

humanscRNA-seq

𝕏 PostBluesky

Developmental BiologybioRxivPreprintDec 17, 2025

Development of the Early Childhood Duodenum across Ancestry, Geography and Environment

Joshua de Sousa Casal, Krishnan Raghunathan, Chelsea Asare…·Jay R. Thiagarajah

The paper creates a cellular and spatial map of the duodenum in children, revealing environmental and developmental influences on intestinal cell states.

1 citation

humanscRNA-seq

𝕏 PostBluesky

Developmental BiologyNature CommunicationsPeer-reviewedJan 11, 2022

Robust differentiation of human enteroendocrine cells from intestinal stem cells

Daniel Zeve, Eric Stas, Joshua de Sousa Casal…·David T. Breault

This study develops a method to differentiate human intestinal stem cells into functional enteroendocrine cells using small molecule targeting of specific signaling pathways.

69 citationstop 3%

humanbulk RNA-seq

𝕏 PostBluesky