Scott J. Gratz

Selective regulation of transsynaptic alignment and postsynaptic assembly by a novel NCAM family synaptic adhesion molecule

This study identifies Elff, an NCAM family member, as critical for postsynaptic assembly and transsynaptic alignment in Drosophila NMJs, revealing specialized roles in synaptic nanoarchitecture.

Neurodegenerative and neurodevelopmental roles for bulk lipid transporters VPS13A and BLTP2 in movement disorders

This study investigates the roles of VPS13A and BLTP2 in movement disorders using Drosophila models, finding distinct neurodegenerative and synaptic effects.

Ca2+ channel and active zone protein abundance intersects with input-specific synapse organization to shape functional synaptic diversity

The paper investigates how VGCC abundance and spatial organization influence synaptic function in Drosophila motor neurons with different release probabilities.

Expanded tRNA methyltransferase family member TRMT9B regulates synaptic growth and function

The paper identifies TRMT9B as a negative regulator of synaptogenesis in Drosophila through genetic screening and biochemical analysis.

The calcium channel subunit α2δ-3 organizes synapses via a novel activity-dependent, autocrine BMP signaling pathway

The paper shows that the calcium channel subunit α2δ-3 enables activity-dependent autocrine BMP signaling at Drosophila NMJs, influencing synapse density, structure, and function.

Endogenous tagging reveals differential regulation of Ca2+ channels at single AZs during presynaptic homeostatic potentiation and depression

The paper uses CRISPR to tag Ca2+ channels in Drosophila and shows they are differentially regulated during presynaptic homeostatic potentiation and depression.