Roberto X. Hernandez

Bichromatic exon-reporters reveal voltage-gated Ca2+-channel splice-isoform diversity across Drosophila neurons in vivo

The paper develops bichromatic fluorescent reporters in Drosophila to study voltage-gated Ca2+-channel splice-isoform diversity across neurons in vivo.

Physiologic and nanoscale distinctions define glutamatergic synapses in tonic vs phasic neurons

The paper identifies physiological and nanoscale differences in glutamatergic synapses between tonic and phasic neurons at the Drosophila neuromuscular junction.

Computational modeling predicts acidic microdomains in the glutamatergic synaptic cleft

The paper models pH dynamics in the synaptic cleft of Drosophila NMJ, showing rapid acidification followed by prolonged alkalinization, resolving the discrepancy between ASIC activation and pH measurements.

Neto-α controls synapse organization and homeostasis at the Drosophila neuromuscular junction

The paper shows Neto-α regulates synapse organization and homeostasis at the Drosophila neuromuscular junction through distinct functions in pre- and postsynaptic compartments.

Endogenous tagging reveals differential regulation of Ca2+ channels at single AZs during presynaptic homeostatic potentiation and depression

The paper uses CRISPR to tag Ca2+ channels in Drosophila and shows they are differentially regulated during presynaptic homeostatic potentiation and depression.