Kate M. O’Connor-Giles

This study identifies Elff, an NCAM family member, as critical for postsynaptic assembly and transsynaptic alignment in Drosophila NMJs, revealing specialized roles in synaptic nanoarchitecture.

This study investigates the roles of VPS13A and BLTP2 in movement disorders using Drosophila models, finding distinct neurodegenerative and synaptic effects.

The paper identifies DEAF1 as a repressor of synaptic genes, showing its role in limiting synaptogenesis and linking it to intellectual disability.

The paper investigates how VGCC abundance and spatial organization influence synaptic function in Drosophila motor neurons with different release probabilities.

This study shows that LRP4 functions presynaptically at Drosophila neuromuscular synapses, organizing development, maturation, and cytoskeletal structure through SRPK79D.

The paper shows PDZD8 promotes autophagy at ER-lysosome contact sites to regulate synaptogenesis through lipid transfer and lysosome maturation.

The paper identifies TRMT9B as a negative regulator of synaptogenesis in Drosophila through genetic screening and biochemical analysis.

The paper shows that the calcium channel subunit α2δ-3 enables activity-dependent autocrine BMP signaling at Drosophila NMJs, influencing synapse density, structure, and function.

The paper uses CRISPR to tag Ca2+ channels in Drosophila and shows they are differentially regulated during presynaptic homeostatic potentiation and depression.