Fanju W. Meng

The splicing kinase PRPF-4 is required for somatic development and germline function in C. elegans

This study investigates the role of PRPF-4, a spliceosomal kinase, in C. elegans development and germline function, showing its essential role in alternative splicing and gene expression.

H2A.Z levels control the timing of major events at the maternal-zygotic transition

This study shows that H2A.Z levels act as a timer for the maternal-zygotic transition in Drosophila and zebrafish, influencing developmental timing through both nuclear and non-nuclear mechanisms.

Anp32e protects against accumulation of H2A.Z at Sox motif containing promoters during zebrafish gastrulation

The paper shows that Anp32e limits H2A.Z accumulation at Sox motif promoters during zebrafish gastrulation, enabling timely gene expression.

Competition for H2A.Z between genes and repetitive elements establishes response to anti-viral immune activation

The paper shows that H2A.Z levels influence sensitivity to retroviral activation by shifting its distribution between gene promoters and repetitive elements in zebrafish embryos.

Identification of chromatin states during zebrafish gastrulation using CUT&RUN and CUT&Tag

The paper applies CUT&RUN and CUT&Tag to zebrafish gastrulation embryos to map chromatin states and identify developmental gene regulation patterns.

Genome-wide Chromatin Accessibility is Restricted by ANP32E

The paper shows ANP32E restricts genome-wide chromatin accessibility by regulating H2A.Z localization in mouse fibroblasts.