Author

Amanda J. Saraf

Riley Hospital for ChildrenORCID 0000-0002-0167-8716Unclaimed ORCID profile · follow to get notified of new preprints

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Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1 Organism:mouse· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Amy C. GrossiD· 1 shared Berkley E. GryderiD· 1 shared Hélène Le PommelletiD· 1 shared James Brandon ReineckeiD· 1 shared John HinckleyiD· 1 shared Kelly M. GutpelliD· 1 shared Leyre Jimenez GarciaiD· 1 shared Maren CamiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Amy C. GrossORCID

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1 paper

Recent·Most cited

Metastasis-initiating osteosarcoma subpopulations establish paracrine interactions with both lung and tumor cells to create a metastatic niche

James Brandon Reinecke, Leyre Jimenez Garcia, Amanda J. Saraf, John Hinckley, Amy C. Gross, Hélène Le Pommellet, Kelly M. Gutpell, Maren Cam, Matthew V. Cannon, Matthew J. Gust, Sophia Vatelle, Berkley E. Gryder, Ruben Dries, Ryan David Roberts

This study identifies metastasis-initiating osteosarcoma subpopulations that interact with lung and tumor cells to form a metastatic niche, highlighting tumor-stromal interactions as key drivers of metastasis.

Cancer Research · Aug 29, 2025Peer-reviewedCancer Biology