Jeroen van der Grond

Genetic variants for head size share genes and pathways with cancer

This study identifies 67 genetic loci associated with head size, finding strong overlaps with cancer pathways and genes, suggesting shared genetic mechanisms between head growth and cancer risk.

Transcriptomic signatures associated with regional cortical thickness changes in Parkinson's disease

The paper identifies gene expression patterns linked to cortical thickness changes in Parkinson's disease using MRI and transcriptomic data, revealing pathways related to cellular maintenance mechanisms.

Cholinergic circuit genes in the healthy brain are differentially expressed in regions that exhibit gray matter loss in Parkinson's disease

The paper identifies gene expression changes in brain regions with gray matter loss in Parkinson's disease and links them to cholinergic circuits and signaling pathways.

Common genetic variation indicates separate etiologies for periventricular and deep white matter hyperintensities

This study identifies genetic loci specific to periventricular and deep white matter hyperintensities, revealing distinct genetic architectures and potential biological mechanisms.

Partial derivatives meta-analysis: pooled analyses when individual participant data cannot be shared

This paper introduces a meta-analytical method that achieves IPD-level results using only aggregate data, enabling robust analysis when individual participant data cannot be shared.