Author

Christophe Grundschober

F. Hoffmann-La Roche AGORCID 0000-0002-0190-9051Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:electronic health records· 2 Approach:experimental assay· 2 Organism:mouse· 2 Organism:rat· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:optimal transport· 1

Frequent Co-Authors

Andries KalsbeekiD· 1 shared Barbara A.M. BiemansiD· 1 shared Bianca D. van GroeniD· 1 shared Chloé HegoburuiD· 1 shared David Mota Caseiro· 1 shared Eric P. M. Prinssen· 1 shared Erwin H. van den BurgiD· 1 shared Frédéric KnoflachiD· 1 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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1 shared paperNeuroscience

Andries KalsbeekORCID

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4 papers

Recent·Most cited

Neurosciencenpj Biological Timing and SleepPeer-reviewedJun 3, 2026

Modelling the effect of V1a receptor antagonism and its potential therapeutic effect in circadian disorders

Marcelo Boareto, Jorge Mendoza, Sebastian C. Holst…·Christophe Grundschober

This paper models the effect of V1a receptor antagonism on circadian rhythms in mice, showing it accelerates resynchronization and suggests therapeutic potential for circadian disorders.

DOI 10.1038/s44323-026-00085-1

mousestatistical model

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NeurosciencebioRxivPreprintAug 30, 2025

Neuromedin U Receptor 2 orchestrates sleep continuity and circadian entrainment

Konstantinos Kompotis, Sabrina Androvic, Miho Sato…·Steven A. Brown

This study shows that NMUR2 antagonism with R-PSOP disrupts sleep continuity and circadian entrainment, with PVH neurons mediating these effects.

DOI 10.1101/2025.08.30.673157

mouseexperimental assay

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NeuroscienceFrontiers in Cellular NeurosciencePeer-reviewedDec 7, 2023

Selective oxytocin receptor activation prevents prefrontal circuit dysfunction and social behavioral alterations in response to chronic prefrontal cortex activation in rats

Philipp Janz, Frédéric Knoflach, Konrad Bleicher…·Madhurima Benekareddy

2 citations

ratelectronic health records

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NeurosciencebioRxivPreprintOct 29, 2023

Social buffering switches fear to safety encoding by oxytocin recruitment of central amygdala "buffer neurons"

Chloé Hegoburu, Yan Tang, Ruifang Niu…·Ron Stoop

This study identifies a neural mechanism by which oxytocin recruits specific CeA neurons to switch fear responses to safety during social buffering in rats.

DOI 10.1101/2023.10.29.563530

ratelectronic health records

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