Silke Braune

Nanoscale imaging resolves canonical topology and intracellular dynamics of SUN5/SPAG4L during mammalian spermiogenesis

This study uses advanced imaging techniques to clarify SUN5's localization and dynamics during spermiogenesis, resolving previous controversies about its structure and function.

A luminal proteome of the endoplasmic reticulum and Golgi apparatus reveals a novel modulator of ER stress tolerance in African trypanosomes

This study maps the luminal proteome of the ER and Golgi in T. brucei using TurboID proximity biotinylation, identifying TbMANF as a novel modulator of ER stress tolerance in African trypanosomes.

The trypanosome mRNA decapping enzyme ALPH1 prefers caps without m7G methylation and produces diphosphate-RNA

This study characterizes the trypanosome mRNA decapping enzyme ALPH1, showing it preferentially cleaves non-m7G-capped RNAs and produces diphosphate-RNA.

A combination of expansion microscopy and proximity labelling reveals conserved and unique asymmetric functional hubs at the trypanosome nuclear pore

The paper uses expansion microscopy and proximity labeling to reveal an asymmetric nuclear pore structure in trypanosomes, identifying unique and conserved components involved in mRNA export.