Bernardo Gabiatti

The RNA helicase KREH2 directly binds the RESC1-RESC2 complex in trypanosomatid mitochondrial RNA editing

This study identifies a direct interaction between the RNA helicase KREH2 and the RESC1-RESC2 complex in trypanosomatid mitochondrial RNA editing using biochemical and structural methods.

Intron-loss in Kinetoplastea correlates with a non-functional EJC and loss of NMD factors

This study shows that Trypanosoma brucei lacks a functional EJC and NMD pathway due to intron loss and gene redundancy.

A combination of expansion microscopy and proximity labelling reveals conserved and unique asymmetric functional hubs at the trypanosome nuclear pore

The paper uses expansion microscopy and proximity labeling to reveal an asymmetric nuclear pore structure in trypanosomes, identifying unique and conserved components involved in mRNA export.

Two distinct Trypanosoma eIF4F complexes co-exist, bind different mRNAs and are regulated during nutritional stress

The paper identifies two distinct eIF4F complexes in Trypanosoma cruzi that bind different mRNAs and show altered associations under nutritional stress.