Farnaz Zahedifard

This study maps the luminal proteome of the ER and Golgi in T. brucei using TurboID proximity biotinylation, identifying TbMANF as a novel modulator of ER stress tolerance in African trypanosomes.

This study identifies CPSF3 as a target of benzoxaboroles in trypanosomatids, showing that BoBs induce sumoylation-dependent degradation of CPSF complex members, leading to reduced mRNA levels.