Author

Al Kline

Centers for Disease Control and PreventionORCID 0000-0002-0201-0291Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Assay:metagenomics· 1 Assay:organoid / primary culture· 1 Assay:proteomics· 1

Frequent Co-Authors

James E. PoseyiD· 2 shared Suraj B. SableiD· 2 shared Wen LiiD· 2 shared Sakthivel GovindarajiD· 1 shared Vijayakumar VeluiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

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2 shared papersBioengineering

James E. PoseyORCID

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2 papers

Recent·Most cited

BioengineeringbioRxivPreprintAug 27, 2025

Methodology for a freshly engineered or cryo-preserved 3D tuberculoma bioplatform for studying tuberculosis biology and high-content screening of therapeutics

Suraj B. Sable, Al Kline, Wen Li, James E. Posey

This paper introduces a 3D tuberculoma bioplatform for studying tuberculosis biology and high-content screening, showing it can generate structured lesions and be scaled for high-throughput use.

1 citation

humanorganoid / primary culture

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ImmunologybioRxivPreprintAug 27, 2025

Identification and characterization of host-directed therapeutics for tuberculosis using a versatile human 3D tuberculoma bioplatform

Suraj B. Sable, Wen Li, Allison Kline…·James E. Posey

This paper develops a 3D bioplatform to screen host-directed therapeutics for tuberculosis, identifying compounds that reduce mycobacterial burdens and granuloma lesions.

4 citations

humanproteomics

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