Author

James E. Posey

Centers for Disease Control and PreventionORCID 0000-0002-3901-8836Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Bioengineering· 1 Genomics· 1 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 3 Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Assay:metagenomics· 1 Assay:organoid / primary culture· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Allison KlineiD· 2 shared Suraj B. SableiD· 2 shared Wen LiiD· 2 shared Aijing Ma· 1 shared Ajit LalvaniiD· 1 shared Alexander S. LachapelleiD· 1 shared Ana Lúıza Gibertoni CruziD· 1 shared Anastasia Sideris KochiD· 1 shared

Activity by Year

2020-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBioengineering

Allison KlineORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

BioengineeringbioRxivPreprintAug 27, 2025

Methodology for a freshly engineered or cryo-preserved 3D tuberculoma bioplatform for studying tuberculosis biology and high-content screening of therapeutics

Suraj B. Sable, Al Kline, Wen Li, James E. Posey

This paper introduces a 3D tuberculoma bioplatform for studying tuberculosis biology and high-content screening, showing it can generate structured lesions and be scaled for high-throughput use.

1 citation

humanorganoid / primary culture

𝕏 PostBluesky

ImmunologybioRxivPreprintAug 27, 2025

Identification and characterization of host-directed therapeutics for tuberculosis using a versatile human 3D tuberculoma bioplatform

Suraj B. Sable, Wen Li, Allison Kline…·James E. Posey

This paper develops a 3D bioplatform to screen host-directed therapeutics for tuberculosis, identifying compounds that reduce mycobacterial burdens and granuloma lesions.

4 citations

humanproteomics

𝕏 PostBluesky

GenomicsMolecular Biology and EvolutionPeer-reviewedMar 10, 2020

GenomegaMap: within-species genome-wide dN/dS estimation from over 10,000 genomes

Daniel J. Wilson, Derrick W. Crook, Tim Peto…·Dick van Soolingen

GenomegaMap estimates genome-wide dN/dS ratios across 10,209 tuberculosis genomes to identify selection pressures shaping the pathogen's evolution.

48 citations

humanwhole-genome sequencing

𝕏 PostBluesky