Takanori Amano

EV-Tracer detects and profiles lineage-specific extracellular vesicles in cancer-fibroblast co-cultures, revealing interferon-related RNA signatures associated with cell-cell contact.

This paper creates a mouse model with a patient-derived LMX1B variant, showing tissue-specific effects of nail-patella syndrome.

This study introduces a genome editing method to rapidly generate and test driver mutations in target genes, identifying novel resistance mutations in lung cancer.

The paper shows that the shh limb enhancer MFCS1 is active in patterned limb regeneration in tadpoles but not in hypomorphic regeneration in froglets, suggesting epigenetic regulation is key.

This study shows that Sonic hedgehog (Shh) is essential for patterning the intrinsic tongue muscles through cranial neural crest-derived mesenchyme in mice.