Keisuke Yoshida

EV-Tracer enables lineage-resolved detection and molecular profiling of extracellular vesicle-associated signals in cancer-fibroblast co-culture

EV-Tracer detects and profiles lineage-specific extracellular vesicles in cancer-fibroblast co-cultures, revealing interferon-related RNA signatures associated with cell-cell contact.

A patient-derived LMX1B variant causes tissue-specific manifestations of nail-patella syndrome in mice

This paper creates a mouse model with a patient-derived LMX1B variant, showing tissue-specific effects of nail-patella syndrome.

Comprehensive and accelerated mapping of driver mutations through single-nucleotide random mutagenesis of target genes

This study introduces a genome editing method to rapidly generate and test driver mutations in target genes, identifying novel resistance mutations in lung cancer.