Jeet H. Patel

This paper shows that an IMPDH2 variant linked to neurodevelopmental disorders disrupts purine biosynthesis and somitogenesis in Xenopus tropicalis by affecting filament assembly and GTP sensitivity.

The paper shows that IMPDH2 is required for tail regeneration in Xenopus tropicalis and forms filaments in regenerating tissue under high GTP demand.

This study identifies Fasnall as a Complex I inhibitor that mimics FASN inhibition, showing anti-tumor effects without neurological side effects.

This study shows Hif1α is required for Wnt-regulated gene expression during Xenopus tropicalis tail regeneration, highlighting its role in posterior specification and differentiation.