Cancer BiologybioRxivPreprint
A trimeric USP11/USP7/TCEAL1 complex stabilizes RNAPII during early transcription to sustain oncogenic gene expression
Markus Dehmer, Peter Gallant, Steffi Herold…·Gabriele Büchel
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University of WürzburgORCID 0000-0002-0216-6026Unclaimed ORCID profile · follow to get notified of new preprints
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Markus Dehmer, Peter Gallant, Steffi Herold…·Gabriele Büchel
Jochen Kuper, Tamsanqa Tafara Hove, Sarah Maidl…·Caroline Kisker
This study uses cryo-EM to reveal how XPD helicase stalls on interstrand crosslinked DNA, identifies functional residues, and suggests a model for NER bubble formation.