Debayan Dey

This study determines the structural basis of Trm10's specific tRNA methylation by capturing its post-catalytic states using cryo-EM and MD simulations.

This study identifies that RsmF activity in E. coli depends on prior modification of 16S rRNA helix 44 by RsmE and RsmH, revealing an order of operations for ribosome biogenesis modifications.

This study determines the cryo-EM structure of the RsmI-30S complex and reveals how RsmI recognizes and modifies the 16S rRNA C1402 nucleotide.

The paper studies the evolutionary and structural characteristics of the HUpb interface in HU proteins and computationally designs inhibitors targeting this interface.