Author

Atsushi Toyoda

Ibaraki UniversityORCID 0000-0002-0245-3244Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:proteomics· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Hideo HagiharaiD· 2 shared Hikari OtabiiD· 2 shared Hirotaka ShojiiD· 2 shared Akiko Hayashi‐TakagiiD· 1 shared Akinobu MatsumotoiD· 1 shared Akio KiharaiD· 1 shared Akito NakaoiD· 1 shared Anja UrbachiD· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersNeuroscience

Hideo HagiharaORCID

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2 papers

Recent·Most cited

Large-scale animal model study uncovers altered brain pH and lactate levels as a transdiagnostic endophenotype of neuropsychiatric disorders involving cognitive impairment

Hideo Hagihara, Hirotaka Shoji, Satoko Hattori, Giovanni Sala, Yoshihiro Takamiya, Mika Tanaka, Masafumi Ihara, Mihiro Shibutani, Izuho Hatada, Kei Hori, Mikio Hoshino, Akito Nakao, Yasuo Mori, Shigeo Okabe, Masayuki Matsushita, , Michihiro Igarashi

The paper investigates brain pH and lactate levels in animal models of neuropsychiatric disorders, finding decreased pH and increased lactate levels as common features across multiple models.

eLife · Sep 1, 2023Peer-reviewedNeuroscience

Protein lactylation induced by neural excitation

Hideo Hagihara, Hirotaka Shoji, Hikari Otabi, Atsushi Toyoda, Kaoru Katoh, Masakazu Namihira, Tsuyoshi Miyakawa

This study shows that lysine lactylation in brain cells is induced by neural excitation and behavioral stimuli, affecting mood-related behaviors.

Cell Reports · Oct 1, 2021Peer-reviewedNeuroscience