Kotaro Kiga

This study reveals the structural mechanism of the type IX Retron-Kva2 anti-phage defense system in Klebsiella variicola, showing how it cleaves host RNAs to inhibit phage infection.

The paper identifies Evangelion, a new family of anti-phage defence systems encoded in antimicrobial-resistance plasmids, through phenotype-guided analysis of a Staphylococcus aureus plasmid.

This study shows that macrophages generate heat through a cell-autonomous mechanism, which reduces their antibacterial function in cold environments.

This study examines genotype dependence of virulence-associated genes in ESBL-producing E. coli from UTI patients, finding ST131 strains show distinct virulence gene repertoires and lower sepsis rates.

This study identifies phage genes that inactivate bacterial immune systems by testing gene deletions in a phage library against bacterial defense systems.