Joseph L. Sottnik

CDH1 loss remodels gene expression and lineage identity in human mammary epithelial cells

This study shows that CDH1 loss in human mammary epithelial cells remodels gene expression and lineage identity toward a luminal progenitor-like state, contributing to ILC oncogenesis.

Advanced models of lobular breast cancer metastasis capture clinical organ tropism, endocrine response, and bone remodeling

This study develops a metastatic ILC mouse model to study organ tropism, endocrine response, and bone remodeling in mILC.

Glutamate-Handling Proteins Associate with Adverse Clinicopathologic Features and Comorbidities in Invasive Lobular Carcinoma

The paper examines glutamate-handling proteins in ILC and finds associations with tumor size, ER expression, and comorbidities, suggesting therapeutic targets.