ImmunologybioRxivPreprint
B Cell Receptor Signaling Sets Boundaries for Selection of Broadly Neutralizing Antibody Functional Mutations
Ankita Singh, Kara M. Anasti, Elizabeth S. Van Itallie…·S. Munir Alam
The paper shows that B cell receptor signaling sets limits on the selection of functional mutations in antibodies, with mid-affinity antigens showing optimal neutralization.
DOI 10.64898/2026.08.13.744461