Author

Claudio Counoupas

The University of SydneyORCID 0000-0002-0283-4004Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 3 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Approach:genetic perturbation / CRISPR· 1 Assay:protein sequence· 1

Frequent Co-Authors

James A. TriccasiD· 4 shared Megan C. SteainiD· 3 shared Sibel AlcaiD· 3 shared Caroline L. AshleyiD· 2 shared Warwick J. BrittoniD· 2 shared Andrea BustamanteiD· 1 shared Andrew H. BuultjensiD· 1 shared Colin William PoutoniD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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4 shared papersImmunology

James A. TriccasORCID

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4 papers

Recent·Most cited

A mobile ESX type VII secretion system enhances intracellular persistence in globally distributed Mycobacterium abscessus

Kia C. Ferrell, Andrew H. Buultjens, Sherridan Warner, Sibel Alca, Andrea Bustamante, Eby Sim, Elena M. Martinez, Vitali Sintchenko, Claudio Counoupas, Timothy Paul Stinear, James A. Triccas

This study identifies a novel plasmid-borne ESX type VII secretion system in M. abscessus that enhances intracellular survival in macrophages.

bioRxiv · Jan 26, 2026 · PreprintMicrobiology

A Single Chimeric Spike Antigen Induces Pan-Sarbecovirus Immunity

Claudio Counoupas, Elizabeth Chan, Paco Pino, Joshua Armitano, Matt D. Johansen, Lachlan J. Smith, Caroline L. Ashley, Eva Estapé, Jean Troyon, Sibel Alca, Stefan Miemczyk, Nicole G. Hansbro, Gabriella M. Scandurra, Warwick J. Britton, Thomas Courant, , James A. Triccas

This study develops a chimeric spike antigen vaccine (CoVEXS5) that induces broad immunity against multiple SARS-CoV-2 variants and other sarbecoviruses in animal models.

npj Vaccines · May 8, 2025Peer-reviewedImmunology

An LNP-mRNA vaccine provides potent immunogenicity and protection against Mycobacterium tuberculosis

Hannah Lukeman, Hareth A. Al-Wassiti, Stewart A. Fabb, Leonard Lim, Trixie Wang, Warwick J. Britton, Megan C. Steain, Colin William Pouton, James A. Triccas, Claudio Counoupas

This study develops an LNP-mRNA vaccine against Mycobacterium tuberculosis that induces strong immune responses and protects mice from infection, with potential for human application.

EBioMedicine · Feb 15, 2025Peer-reviewedImmunology

Optimisation of a multiplexed, high throughput assay to measure neutralising antibodies against SARS-CoV-2 variants.

Caroline L. Ashley, Malik Bloul, Sibel Alca, Lachlan Smith, Wang Jin, David S. Khoury, Claudio Counoupas, Miles P. Davenport, James A. Triccas, Megan C. Steain

The paper develops a multiplexed, high-throughput pseudovirus neutralisation assay to measure neutralising antibodies against SARS-CoV-2 variants, showing reliability and consistency across single and multiplexed formats.

Journal of Virological Methods · Nov 16, 2024Peer-reviewedImmunology