Author

Xuebin Liao

Center for Life SciencesORCID 0000-0002-0290-894XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

Chi HeiD· 2 shared Hong WuiD· 2 shared Tantan Wang· 2 shared Dan LiiD· 1 shared Dimiter Stanchev DimitroviD· 1 shared Hui ShiiD· 1 shared Liangliang WangiD· 1 shared Liuqing YangiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersImmunology

Chi HeORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

KDM5A enhances MHC-I antigen presentation and potentiates antitumor immunity unleashed by immune checkpoint blockade

Dan Li, Chi He, Zhao-Li Tan, Tantan Wang, Hong Wu, Pengcheng Zuo, Dimiter Stanchev Dimitrov, Liangliang Wang, Xuebin Liao

This study shows KDM5A enhances MHC-I antigen presentation and improves antitumor immunity in response to PD-1 checkpoint blockade in cancer patients.

bioRxiv · Jun 5, 2025 · PreprintImmunology

Enhance Memory CD8+ T Cell Formation via Downregulation of Hematopoietic Progenitor Kinase 1 and Sustained Mitochondrial Fitness

Liuqing Yang, Tantan Wang, Xiangna Guan, Chi He, Hui Shi, Hong Wu, Xuebin Liao

This study shows that HPK1 deletion enhances memory CD8+ T cell formation and antitumor activity by promoting metabolic reprogramming and mitochondrial fitness.

bioRxiv · Apr 10, 2025 · PreprintImmunology