Andreas Stephanou

The paper shows that in mixed E-qM breast tumors, qM cancer cells create immunosuppressive niches leading to MHC-I downregulation and immune evasion.

The paper analyzes canine glioma samples to reveal heterogeneous intratumoral niches with distinct cell plasticity and immunosuppression patterns, highlighting similarities to human gliomas.

This study uses single-nucleus RNA-seq to identify unique neuroepithelial features in canine acanthomatous ameloblastoma, revealing ERBB4 as a therapeutic target.

This study uses single-cell RNA sequencing to show that SOCE blockers BTP2 and CM4620 reduce cytotoxicity in CD8 T cells and NK cells while preserving anti-inflammatory programs in CD4 Tregs.

The paper generates a spatiotemporal atlas of heart development using flow perturbations and spatial transcriptomics to study how blood flow affects cellular, structural, and metabolic remodeling.

The paper shows that disrupting the spliceosome upregulates NMD targets, with some spliceosome components directly affecting NMD.

This study uses single-nucleus multi-omics to analyze fibrolamellar carcinoma, revealing rewired cell communication and potential therapeutic targets.