Author

Jacek Plewka

Jagiellonian UniversityORCID 0000-0002-0307-0907Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:virus· 1

Frequent Co-Authors

Adrien DelpaliD· 1 shared Alex MatsudaiD· 1 shared Anna CzarnaiD· 1 shared Colin Robinson· 1 shared Craig D. L. SmithiD· 1 shared Duncan E. ScottiD· 1 shared Edcon ChangiD· 1 shared Eric J. SnijderiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Adrien DelpalORCID

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1 paper

Recent·Most cited

BiochemistryRSC Medicinal ChemistryPeer-reviewedJan 1, 2026

Crystallographic characterisation and development of bi-substrate inhibitors of coronavirus nsp14 methyltransferase

Irene Georgiou, Colin Robinson, Sean N. O’Byrne…·Ian Hugh Gilbert

The paper develops bi-substrate inhibitors of SARS-CoV-2 nsp14 methyltransferase using structure-guided design, achieving nanomolar potency but limited cellular antiviral activity.

2 citations

virusexperimental assay