Experience from an HTS campaign: Investigation of susceptibility and rescue of SARS-CoV-2 nsp3 protease assay from metal contamination
Irene Georgiou, Sandra O’Neill, Colin Robinson, Fraser Cunningham, Sean N. O’Byrne, David W. Gray, Ian Hugh Gilbert, Duncan E. Scott
The paper investigates false positives in SARS-CoV-2 nsp3 protease HTS assays caused by metal contamination and identifies copper and palladium as primary contaminants.
SLAS TECHNOLOGY · Mar 13, 2026Peer-reviewedBiochemistry