Author

Jana L. Jacobs

University of PittsburghORCID 0000-0002-0322-585XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Elias Konstantine HalvasiD· 2 shared John M. CoffiniD· 2 shared John W. MellorsiD· 2 shared Mary F. KearneyiD· 2 shared Michael J. BaleiD· 2 shared Michele D. Sobolewski· 2 shared Wei ShaoiD· 2 shared Adam A. CapoferriiD· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersMicrobiology

Elias Konstantine HalvasORCID

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2 papers

Recent·Most cited

MicrobiologyProceedings of the National Academy of SciencesPeer-reviewedAug 27, 2024

HIV-1 control in vivo is related to the number but not the fraction of infected cells with viral unspliced RNA

Adam A. Capoferri, Ann P. Wiegand, Feiyu F. Hong…·Mary F. Kearney

The paper compares the fraction and total number of HIV-infected cells with unspliced RNA in controllers and non-controllers, finding that viremic control is linked to fewer infected cells, not a lower fraction of infected cells with HIV usRNA.

7 citations

humanbulk RNA-seq

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GenomicsJournal of Clinical InvestigationPeer-reviewedOct 4, 2020

HIV-1 Viremia Not Suppressible By Antiretroviral Therapy Can Originate from Large T-Cell Clones Producing Infectious Virus

Elias Konstantine Halvas, Kevin W. Joseph, Leah D. Brandt…·John W. Mellors

The paper identifies large T-cell clones producing infectious HIV-1 virus as a source of non-suppressible viremia despite ART adherence and no drug resistance.

141 citationstop 1%

humanexperimental assay

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