Author

Jeffrey S. Miller

University of MinnesotaORCID 0000-0002-0339-4944Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 4 Research Focus:host-pathogen & immune response· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:flow cytometry· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Aaron KhaimrajiD· 1 shared Alberto OriolesiD· 1 shared Alexander K. JohnsoniD· 1 shared Aline PfefferleiD· 1 shared Alka KhaitaniD· 1 shared Anders J. LindstedtiD· 1 shared Anders W. MatsoniD· 1 shared Angela Panoskaltsis‐MortariiD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperImmunology

Aaron KhaimrajORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Pre-treatment Microbiome Diversity and Function is associated with Expansion of Cytotoxic and Regulatory Immune Populations after N-803 treatment in People with HIV

Ashma Chakrawarti, Ross T. Cromarty, Christopher M. Basting, Jodi L. Anderson, Ty A. Schroeder, Kevin Escandón-Vargas, Robin R. Shields‐Cutler, Robert Langat, Erik Swanson, Patrick Soon‐Shiong, Jeffrey T. Safrit, Leonard S. Sender, Sandeep K. Reddy, Jeffrey S. Miller, Joshua Rhein, , Nichole R. Klatt

This study shows that pre-treatment gut microbiome diversity in HIV patients correlates with immune activation and reduced HIV RNA+ cells after N-803 treatment.

bioRxiv · Oct 1, 2025 · PreprintMicrobiology

Toggling of NKG2A expression drives functional specialization of iPSC-derived CAR NK cells

Minoru Kanaya, Camille Philippon, Herman Netskar, Michelle Sætersmoen, Artur Cieślar‐Pobuda, Lamberto Torralba‐Raga, Giovanna Perinetti Casoni, Quirin Hammer, Marianna Vincenti, Merete Thune Wiiger, Silje Zandstra Krokeide, Hanna Julie Hoel, Eivind Heggernes Ask, Mizuha Kosugi‐Kanaya, Lise Kveberg, , Karl‐Johan Malmberg

This study shows that NKG2A expression in iPSC-derived NK cells drives functional specialization, enhancing cytotoxicity and IFN-γ production independent of HLA-E interactions.

bioRxiv · Aug 20, 2025 · PreprintImmunology

Antibody-mediated cellular responses are dysregulated in Multisystem Inflammatory Syndrome in Children (MIS-C)

Jenna K. Dick, Jules A. Sangala, Venkatramana Divana Krishna, Aaron Khaimraj, Lydia Hamel, Spencer M Erickson, Dustin Hicks, Yvette Soigner, Laura E Covill, Alexander K. Johnson, Michael J. Ehrhardt, Keenan Ernste, Petter Brodin, Richard A. Koup, Alka Khaitan, , Geoffrey T. Hart

This study identifies dysregulated antibody-mediated cellular responses in MIS-C, linking NK cell dysfunction to immune pathology and suggesting potential therapeutic interventions.

Journal of the Pediatric Infectious Diseases Society · Oct 1, 2024Peer-reviewedImmunology

Enhanced IL-15-mediated NK cell activation and proliferation by an ADAM17 function-blocking antibody involves CD16A, CD137, and accessory cells

Anders W. Matson, Robert Hullsiek, Kate J. Dixon, Sam C. Wang, Anders J. Lindstedt, Ryan R. Friess, Shee Kwan Phung, Tanya S. Freedman, Martin Felices, Emily Nestor Truckenbrod, Jianming Wu, Jeffrey S. Miller, Bruce K. Walcheck

This study shows that an ADAM17-blocking antibody enhances IL-15-mediated NK cell activation and proliferation through CD16A and CD137, with potential therapeutic applications in cancer.

Journal for ImmunoTherapy of Cancer · Jul 1, 2024Peer-reviewedImmunology