Joshua Rhein

Ongoing lymphoid HIV production drives pyroptosis and GLP-1 counter-regulation in ART-suppressed infection

The paper shows that residual HIV production in lymph nodes of ART-suppressed individuals drives pyroptosis and is counter-regulated by GLP-1 upregulation in the ileum.

Pre-treatment Microbiome Diversity and Function is associated with Expansion of Cytotoxic and Regulatory Immune Populations after N-803 treatment in People with HIV

This study shows that pre-treatment gut microbiome diversity in HIV patients correlates with immune activation and reduced HIV RNA+ cells after N-803 treatment.

DNA methylation patterns associated with prior tuberculosis infection in people with HIV: a pilot cross-sectional study

This study identifies DNA methylation changes in people with HIV with and without prior tuberculosis infection, linking them to pathways involved in neural function, cardiovascular health, and cancer risk.