Mark E. Mikkelsen

This study benchmarks how different anatomical segmentation tools affect MRS-derived metabolite concentration estimates in brain imaging.

This study compares the test-retest reliability of HERMES and HERCULES multi-metabolite editing methods using PRESS and sLASER for volume localization in MRS.

The paper compares RF coil combination methods for MRS data, finding that noise-decorrelation methods improve SNR for detecting low concentration metabolites like GABA.

This study shows that tDCS applied to prefrontal cortex regions modulates self-reported emotions and metabolite levels during a donation task.

The paper introduces NIfTI-MRS, a standardized format for magnetic resonance spectroscopy data to improve sharing and integration across the MRS community.

The paper compares seven algorithms for modelling GABA-edited 1H-MRS data from 222 subjects across 20 sites, finding moderate agreement and highlighting the need for standardized parameters.

This study finds higher brain glutathione levels in older adults and links sensorimotor GSH to poorer motor performance, suggesting age-related antioxidant upregulation.