Meghan A. Turner

The paper uses live-imaging and computational modeling to show that Dorsal hub formation in Drosophila embryos depends on TF-DNA binding kinetics, not enhancer sequence or higher-order regulatory structures.

The paper introduces SACCELERATOR, a framework for spatially aware clustering that improves benchmarking by incorporating expert feedback and consensus analysis across diverse datasets.

The paper quantifies Dorsal concentration, binding, and mobility in Drosophila embryos, revealing threshold-based formation of DNA-bound and mobile clusters linked to gene regulation.

The paper defines major axes of human basal ganglia astrocyte specialization using a multimodal atlas and identifies enhancer code for targeted viral tools.

The paper creates a cross-species consensus atlas of primate basal ganglia cell types using multiomic data from human, macaque, and marmoset, identifying 61 conserved cell types and a novel hybrid medium spiny neuron type.

This paper creates a cross-species spatial transcriptomic atlas of the basal ganglia in human, rhesus macaque, and common marmoset, revealing conserved molecular organization and cell type-specific compartments.

The paper presents a spatially resolved transcriptomic and gene regulatory atlas of primate subcortical regions, revealing spatially tuned transcriptional and regulatory programs across cell types.

The paper introduces THALMANAC, a resource for analyzing single-cell transcriptomic data of the thalamus, revealing gene expression patterns that support and refine thalamic nucleus parcellation.

The paper introduces four new fluorescent protein fusions for Dorsal to study its dynamics in fruit fly embryos.

The paper develops a method to generate variant libraries in vivo using base editing to study gene regulatory programs in multicellular organisms.

The paper uses a minimal synthetic enhancer in Drosophila to show that a single Dorsal binding site can regulate transcriptional engagement probability and timing in response to a morphogen gradient.