Author

Lei Wang

Agricultural Genomics Institute at ShenzhenORCID 0000-0002-0356-3592Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Lei Wang36 papers · The University of Texas Southwestern Medical Center

Biology Disciplines

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Cancer Biology· 1 Genomics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Organism:plant (other)· 1

Frequent Co-Authors

Hui Shen· 2 shared Abhijit ParoliaiD· 1 shared Angela Zhang· 1 shared Arul M. ChinnaiyaniD· 1 shared Baihe CheniD· 1 shared Bo Liu· 1 shared Chen ZhengiD· 1 shared Delin MoiD· 1 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersCancer Biology

Hui Shen

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Single-Atom Modification Enables Reversal of Degradation Selectivity between NSD2 and GSPT1

Weizhong Shen, Yihan Liu, Lianchao Liu, Yingfan Liu, Yan Zhang, Yihan Chen, Lei Wang, Zhiyi Zhou, Angela Zhang, Hui Shen, Fengtao Zhou, Weixue Huang, Xiaomei Ren, Abhijit Parolia, Yong Xu, , Ke Ding

This study modifies a molecule to create two variants with different target selectivity, showing how small structural changes can control degradation activity.

Journal of Medicinal Chemistry · Oct 4, 2026Peer-reviewedCancer Biology

Gq-pathway activation in hippocampal CA1 astrocytes rescues ischemia-induced memory deficits and synaptic plasticity

Yujie Chen, Lei Wang, Jiayao Wang, Yiqi Zhou, Hui Shen, Yuguang Wang, Wei Qin, Bo Liu, Baihe Chen, Yiting Huang, Wenting Guo, Huisen Xu, Qian Tian, Chen Zheng

This study shows that activating the Gq pathway in hippocampal astrocytes improves memory and synaptic plasticity after stroke in mice.

bioRxiv · Jun 16, 2026 · PreprintNeuroscience

Multi-omics analysis reveals signatures of selection and loci associated with complex traits in pigs

Guoqiang Yi, Lei Liu, Yilong Yao, Yuwen Liu, Jiang Li, Yalan Yang, Lingzhao Fang, Delin Mo, Longchao Zhang, Yonggang Liu, Yongchao Niu, Liyuan Wang, Xiaolu Qu, Zhangyuan Pan, Lei Wang, , Zhonglin Tang

This study identifies selection signatures and loci associated with complex traits in pigs by analyzing multi-omics data from Eastern and Western breeds.

bioRxiv · Sep 19, 2023 · PreprintGenomics