The translatome of quiescent Plasmodium falciparum gametocytes reveals parasite pyridoxal 5'-phosphate (PLP) biosynthesis is essential for efficient mosquito stage development
Eduardo Alves, Jack W. Houghton, Lindsay B. Stewart…·Michael J. Delves
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London School of Hygiene & Tropical MedicineORCID 0000-0002-0363-8558Unclaimed ORCID profile · follow to get notified of new preprints
8 papers
Recent·Most cited
Eduardo Alves, Jack W. Houghton, Lindsay B. Stewart…·Michael J. Delves
Samuel Palmer, Balotin Fogang, Lindsay B. Stewart…·David J. Conway
The paper identifies large deletion variants in the PIMMS43 gene of Plasmodium falciparum and shows their geographic frequency variation and potential vector-specific selection.
Nina Billows, Mia L. White, Joseph Thorpe…·Susana G. Campino
The paper presents the first chromosome-scale genome assembly for Dermacentor reticulatus, revealing a repeat-rich genome and providing insights into its phylogenetic placement and functional genomics.
Mojca Kristan, Holly Acford-Palmer, Mónica Campos…·Louisa Alexandra Messenger
This study validates the use of environmental DNA (eDNA) for detecting and characterizing Anopheles stephensi and Aedes aegypti mosquitoes from larval breeding sites using multiplex TaqMan assays and amplicon-sequencing panels.
Anne Meiwald, Emma Clark, Mojca Kristan…·Louisa Alexandra Messenger
The paper assesses insecticide resistance in Anopheles coluzzii, finding over-expression of CYP6P4, CYP6P3, and CYP6Z1 linked to reduced LLIN efficacy and pyrethroid resistance.
Caleb J. Stica, Claire Louise Jeffries, Seth R. Irish…·Louisa Alexandra Messenger
The paper assesses insecticide resistance in Anopheles gambiae s.l. in Faranah, Guinea, identifying resistance to permethrin and deltamethrin and mutations linked to resistance mechanisms.
James Orsborne, Luis Furuya-Kanamori, Claire L. Jeffries…·Laith Yakob
This study systematically reviews and meta-analyzes the human blood index (HBI) of major African malaria vectors, finding higher HBI in Anopheles gambiae and An. funestus compared to An. arabiensis, with location being a stronger predictor than species.
James Orsborne, Luis Furuya-Kanamori, Claire L. Jeffries…·Laith Yakob
The paper introduces a method to assess blood-host plasticity and dispersal rate of Anopheles coluzzii using blood-meal source detection and molecular analysis.